Thermo Fisher Scientific ROS1 Polyclonal Antibody
ROS1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에서 1:500~1:2,000 희석 비율로 사용 가능. 인간 및 랫트 시료 반응. 친화 크로마토그래피로 정제된 액상 항체로, PBS/glycerol 버퍼에 보존. 연구용으로 ROS1 신호전달 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ROS1 (Accession P08922), corresponding to amino acid residues D2249–S2299 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853939 |
Product Specific Information
Antibody detects endogenous levels of total ROS.
Target Information
ROS1 is a tyrosine kinase that functions as a growth or differentiation factor receptor. Protein kinases transfer a phosphate group from ATP to substrate proteins, mediating most signal transduction in eukaryotic cells. They regulate metabolism, transcription, cell cycle, cytoskeletal dynamics, apoptosis, and differentiation.
The tyrosine kinase (TK) group is mainly involved in regulating cell-cell interactions such as differentiation, adhesion, motility, and death. Approximately 90 TK genes have been sequenced, including receptor TK families (EGFR, EPH, FGFR, PDGFR, TRK, VEGFR) and cytosolic TK families (ABL, FAK, JAK, SRC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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