Thermo Fisher Scientific Cdc42GAP Polyclonal Antibody
Cdc42GAP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. IHC 및 IHC-P에 사용 가능하며 Human과 Mouse에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, TBS 버퍼에 0.09% sodium azide를 포함. 연구용 전용.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human CDC42 GTPase-activating protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Guinea pig, Orangutan, Monkey, Chimpanzee, Northern white-cheeked gibbon, and Little brown bat.
Target Information
The p190 RhoGAP protein is associated with p120 RasGAP in growth-factor stimulated and tyrosine kinase transformed cells. It functions as a GTPase-activating protein (GAP) for Rho and Rac family proteins, which are involved in regulating cytoskeletal actin and membrane ruffling. The antibody appears to couple signal transduction via Ras and Rho through its association with RasGAP. The presence of two adjacent SH2 domains in the p21 RAS GAP indicates that GAP might interact directly with tyrosine kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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