Thermo Fisher Scientific C17orf104 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human C17orf104. Recombinant protein control fragment (Product #RP-93482). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:C17orf104,uniProtId:A2RUB1-4,ncbiNodeId:9606,antigenRange:535-668,antigenLength:952,antigenImageFileName:PA5-55561_C17orf104_A2RUB1-4_Rabbit.svg,antigenImageFileNamePDP:PA5-55561_C17orf104_A2RUB1-4_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638811

Product Specific Information

Immunogen sequence: YCQENPSAFS SFDFSYSGAE RIQSVNHIEG LTKPGEENLF KLVTDKKIKQ PNGFCDNYSA QKYGIIENVN KHNFQAKPQS GHYDPEEGPK HLDGLSQNTY QDLLESQGHS NSHRTRGGDN SRVNRTQVSC FSNN

Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.

Target Information

Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.