Thermo Fisher Scientific TESK2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human TESK2, validated for IHC and ICC/IF applications. High specificity recombinant immunogen-based antibody for research use. Suitable for studies on spermatogenesis and actin regulation.
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Thermo Fisher Scientific TESK2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TESK2. Recombinant protein control fragment (Product #RP-89769). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648386 |
Product Specific Information
Immunogen sequence:
TLEEILSRLQ EEEQERDRKL QPTARGLLEK APGVKRLSSL DDKIPHKSPC PRRTIWLSRS QSDIFSRKPP RTVSVLDPYY RPRDGAARTP KVNPFSARQD LMGGKIKFFD LPSKSVISLV F
Highest antigen sequence identity to orthologs:
- Mouse: 88%
- Rat: 90%
Target Information
TESK2 (testis-specific kinase 2) is a serine/threonine protein kinase belonging to the TESK subgroup of the LIMK/TESK family. It contains an N-terminal kinase domain structurally similar to testis-specific protein kinase-1 and LIMK family kinases. TESK2 is mainly expressed in testis and prostate and plays a key role in spermatogenesis. It phosphorylates cofilin at Ser-3, promoting actin stress fiber and focal adhesion formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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