Thermo Fisher Scientific PLAA Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence:
  TGAGRYVPGS ASMGTTMAGV DPFTGNSAYR SAASKTMNIY FPKKEAVTFD QANPTQILGK LKELNGTAPE EKKLTEDDLI LLEKILSLIC
• Highest antigen sequence identity to the following orthologs:
  Mouse – 92%, Rat – 92%

Target Information

Phospholipase A-2-activating protein (PLAA), also named PLAP, interacts with ubiquitin and is involved in maintaining ubiquitin levels. PLAA contains multiple consensus domains including WD repeats, PFU domain, and PUL domain. Although its function remains unclear, ubiquitin binding of PLAA may play a central role connecting ubiquitination and degradation in ERAD. Recent findings indicate PLAA acts as a novel nociceptive mediator after incision, regulated by miR-203.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.