Thermo Fisher Scientific PLAA Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PLAA. Recombinant protein control fragment (Product #RP-92983). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PLAA,uniProtId:Q9Y263-1,ncbiNodeId:9606,antigenRange:397-493,antigenLength:795,antigenImageFileName:PA5-54300_PLAA_Q9Y263-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54300_PLAA_Q9Y263-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645619

Product Specific Information

Immunogen sequence: EGKEFDYVFS IDVNEGGPSY KLPYNTSDDP WLTAYNFLQK NDLNPMFLDQ VAKFIIDNTK GQMLGLGNPS FSDPFTGGGR YVPGSSGSSN TLPTADP

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Target Information

Phospholipase A-2-activating protein (PLAA), also named PLAP, can interact with ubiquitin and is involved in the maintenance of ubiquitin levels. PLAA contains multiple consensus domains including WD repeats, PFU domain and PUL domain. Although the function of PLAA remains unclear, ubiquitin binding of PLAA might be the central role that connects ubiquitination and degradation in ERAD. Recent finding revealed that PLAA served as a novel nociceptive mediator after incision, and its expression level is regulated by miR-203.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.