Thermo Fisher Scientific PLAA Polyclonal Antibody
PLAA 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. Western blot, IHC(P), ICC/IF에 사용 가능하며 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액 형태로 제공되며, 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PLAA. Recombinant protein control fragment (Product #RP-92983) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645619 |
Product Specific Information
Immunogen sequence:
EGKEFDYVFS IDVNEGGPSY KLPYNTSDDP WLTAYNFLQK NDLNPMFLDQ VAKFIIDNTK GQMLGLGNPS FSDPFTGGGR YVPGSSGSSN TLPTADP
Antigen sequence identity:
Mouse – 92%, Rat – 92%
Target Information
Phospholipase A-2-activating protein (PLAA), also named PLAP, can interact with ubiquitin and is involved in the maintenance of ubiquitin levels. PLAA contains multiple consensus domains including WD repeats, PFU domain, and PUL domain. Although the function of PLAA remains unclear, ubiquitin binding of PLAA might be the central role that connects ubiquitination and degradation in ERAD. Recent findings revealed that PLAA serves as a novel nociceptive mediator after incision, and its expression level is regulated by miR-203.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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