
Thermo Fisher Scientific ERCC1 Recombinant Rabbit Monoclonal Antibody (23GB1230)
ERCC1 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot 및 Immunocytochemistry에 적합. HEK293F 발현 시스템 기반, 높은 특이성과 재현성 제공. 인간 및 생쥐 시료 반응. 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB1230 |
| Immunogen | A synthesized peptide derived from human ERCC1 (1–180AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′-incision during DNA repair. It functions with SLX4 in the first step of interstrand cross-link (ICL) repair and participates in processing anaphase bridge-generating DNA structures, which can lead to cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks in conjunction with SLX4. (Source: Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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