Thermo Fisher Scientific GSTM5 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

• Positive Samples: Mouse heart, Mouse kidney, Mouse liver, Rat testis, Rat brain
• Immunogen sequence:
  LENQVMDNHM ELVRLCYDPD FEKLKPKYLE ELPEKLKLYS EFLGKRPWFA GDKITFVDFL AYDVLDMKRI FEPKCLDAFL NLKDFISRFE GLKKISAYMK SSQFLRGLLF GKSATWNSK

Target Information

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Eight distinct classes of soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
This gene encodes a glutathione S-transferase that belongs to the mu class, functioning in detoxification of electrophilic compounds including carcinogens, therapeutic drugs, environmental toxins, and oxidative stress products by conjugation with glutathione.
The mu class genes are organized in a cluster on chromosome 1p13.3 and are highly polymorphic, affecting susceptibility to carcinogens and drug efficacy. Diversification occurs in substrate-binding domains and tissue expression patterns to handle a wide range of foreign compounds.

⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.