Thermo Fisher Scientific SERPINA3 Recombinant Rabbit Monoclonal Antibody (006)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:5,000–1:10,000

Product Specifications

Additional Formats

• HRP
• Request custom conjugation

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for Human SerpinA3.

Target Information

SERPINA encodes Alpha 1-ACT, an early-stage acute-phase plasma protein and serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT is a serine protease inhibitor associated with amyloid plaques in Alzheimer’s disease (AD) and aged human and monkey brain. Regulation of serine proteases and their inhibitors plays an important role in neuromuscular differentiation. PSA, a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.