Thermo Fisher Scientific SERPINA5 Recombinant Rabbit Monoclonal Antibody (110)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to the larger rabbit immune repertoire

This antibody has specificity for Human SerpinA5.

Target Information

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. It is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), acting as an inhibitor of fibrinolysis.

Defects in this gene cause plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of its product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.