Thermo Fisher Scientific MASTL Polyclonal Antibody
Thermo Fisher Scientific의 MASTL Polyclonal Antibody는 인간 및 생쥐 시료에서 MASTL 단백질을 검출하는 고품질 항체입니다. Western blot과 Immunocytochemistry에 적합하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 보장합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MASTL (Accession Q96GX5), corresponding to amino acid residues K830–L879 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854193 |
Product Specific Information
Antibody detects endogenous levels of total MASTL.
Target Information
MASTL (microtubule associated serine/threonine kinase-like) belongs to the MAST family, AGC Ser/Thr protein kinase group.
MASTL promotes mitotic progression and cell cycle reentry after DNA damage.
Loss of MASTL leads to defects in chromosome condensation, separation, and other aspects of mitotic progression, primarily mediated by inhibiting PP2A/B55 delta.
Overexpression of MASTL is correlated with cancer progression, poor patient survival, and tumor recurrence in various cancers.
Mutations at this locus have been associated with autosomal dominant thrombocytopenia (thrombocytopenia-2).
Alternatively spliced transcript variants have been described for this locus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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