Thermo Fisher Scientific S100A4/Metastasin/Calvasculin (Marker of Tumor Metastasis) Monoclonal Antibody (S100A4/1481), Biotin
S100A4 단백질을 표적으로 하는 종양 전이 마커 단일클론 항체로, Western blot, IHC, ICC, Flow Cytometry 등 다양한 응용에 적합. Biotin 결합형으로 높은 특이성과 재현성을 제공하며, 인간 및 마우스 시료에 반응. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S100A4/1481 |
| Immunogen | Recombinant fragment (around aa 1–101) of human S100A4 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the S100A4 gene is a member of the S100 family of proteins containing two EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in regulating cellular processes such as cell cycle progression and differentiation.
S100 genes include at least 13 members located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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