Thermo Fisher Scientific CYP2A6 Polyclonal Antibody
Rabbit polyclonal antibody against human CYP2A6 for Western blot applications. Targets amino acids 312–406 of CYP2A6. Supplied as a liquid, unconjugated form at 1 mg/mL. Ideal for drug metabolism and cytochrome P450 research.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 312–406 of Human CYP2A6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 40% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2545366 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLaS3
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
Target Information
CYP2A6 encodes a member of the cytochrome P450 superfamily of enzymes. These monooxygenases catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. The protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. CYP2A6 hydroxylates coumarin and metabolizes nicotine, aflatoxin B1, nitrosamines, and certain pharmaceuticals. Individuals with specific allelic variants may exhibit poor metabolizer phenotypes. The gene is part of a large cluster of cytochrome P450 genes (CYP2A, CYP2B, CYP2F) on chromosome 19q and was formerly referred to as CYP2A3.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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