Thermo Fisher Scientific IFRD1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1.0-4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

5 µg/mL

-

Product Specifications

Species Reactivity

Bovine, Dog, Human, Mouse, Non-human primate, Pig

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A portion of amino acids 70-120 of human Tis7 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IFRD1,uniProtId:O00458-1,ncbiNodeId:9606,antigenRange:70-120,antigenLength:451,antigenImageFileName:PA5-23279_IFRD1_O00458-1_Rabbit.svg,antigenImageFileNamePDP:PA5-23279_IFRD1_O00458-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2540803

Target Information

Tis7, also known as IFRD1, is a 442 amino acid containing membrane associated, non-nuclear intracellular protein belonging to the IFRD family. A regulatory protein expressed in a variety of tissues, Tis7 is known to play an important role in the regulation of gene activity in the proliferative and/or differentiative pathways induced by NGF. Reports suggest that Tis7 may be an autocrine factor that attenuates or amplifies the initial ligand induced signal and might also augment the adaptive response by stimulating the production of differentiated enterocytes. Tis7 acts as a negative regulator of transcriptional activity and represses expression of genes involved in myogenesis, muscle maintenance, and regeneration in a histone deacetylase dependent manner.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.