Thermo Fisher Scientific IFRD1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human IFRD1 (Tis7) for WB and IHC applications. Reacts with multiple species including human, mouse, and pig. Purified via Protein A, supplied in PBS with BSA and sodium azide. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.0–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Bovine, Dog, Human, Mouse, Non-human primate, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acids 70–120 of human Tis7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540803 |
Target Information
Tis7, also known as IFRD1, is a 442-amino-acid membrane-associated, non-nuclear intracellular protein belonging to the IFRD family. It is a regulatory protein expressed in various tissues and plays an important role in gene activity regulation within proliferative and differentiative pathways induced by NGF. Tis7 may act as an autocrine factor that modulates ligand-induced signaling and supports adaptive responses by stimulating the production of differentiated enterocytes. It functions as a negative regulator of transcriptional activity and represses genes involved in myogenesis, muscle maintenance, and regeneration in a histone deacetylase-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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