Thermo Fisher Scientific CENPJ Polyclonal Antibody
Rabbit polyclonal antibody specific for human CENPJ protein. Validated for immunocytochemistry (ICC/IF) at 0.25–2 µg/mL. Purified by antigen affinity chromatography and supplied in PBS with 40% glycerol. Suitable for research use in centrosome and spin...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Category | Specification |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CENPJ. Recombinant protein control fragment (Product #RP-107007) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664836 |
Product Specific Information
Immunogen sequence:
DRERGISSRED SPQVCDDKGP FKDTRTQEDK RRDVDLDLSD KDYSSDESIM ESIKHKVSEP SRSSSLSLSK MDFDDERTWT DLEENLCNHD VVLGNESTYG TPQTCYPNNE IGILDKTIKR KIAPVK
Highest antigen sequence identity to orthologs: mouse 64%, rat 60%.
Target Information
The CENPJ gene encodes a protein that is part of the centromere protein family. During cell division, this protein plays a structural role in maintaining centrosome integrity and spindle morphology, and is involved in microtubule disassembly at the centrosome. It can function as a transcriptional coactivator in the Stat5 signaling pathway, and as a coactivator of NF-kappaB-mediated transcription through interaction with p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, characterized by reduced brain size and mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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