Thermo Fisher Scientific NOD4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NOD4 protein for ICC/IF applications. Recombinant human NOD4 immunogen, antigen affinity purified, unconjugated liquid form. Provides high specificity for innate immune pathway studies and NF-κB regulation res...
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NOD4. Recombinant protein control fragment (Product #RP-107006) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663914 |
Product Specific Information
Immunogen Sequence:
QHLRVLHLPFS HLGPGGALSL AQALDGSPHL EEISLAENNL AGGVLRFCME LPLLRQIDLV SCKIDNQTAK LLTSSFTSCP ALEVILLSWN LLGDE
Highest antigen sequence identity to orthologs:
- Mouse: 68%
- Rat: 65%
Target Information
NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins involved in innate immune defense. It contains a CARD-like domain, a central NOD domain, and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and antiviral defense mechanisms. As a negative regulator of NF-kappa-B and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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