Thermo Fisher Scientific MAP2K4 Monoclonal Antibody (OTI8A8), TrueMAB
MAP2K4 단백질을 인식하는 Mouse Monoclonal Antibody (Clone OTI8A8)로, WB, IHC, ICC, Flow, IP 등 다양한 응용에 적합. Human 및 Dog 반응성 확인. 고순도 Affinity chromatography 정제, 안정적인 PBS/BSA/glycerol buffer 제공.
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Thermo Fisher Scientific MAP2K4 Monoclonal Antibody (OTI8A8), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A8 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human MAP2K4 expression vector |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.36 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAP2K4 (MEK4) is a serine/threonine kinase of the STE7 family that phosphorylates and activates JNK1, JNK2, and p38. It preferentially phosphorylates the tyrosine residue of JNKs and mediates cellular stress and inflammatory cytokine responses. MAP2K4 plays a role in carcinogenesis; loss-of-function mutations have been identified in lung and pancreatic tumors, while pro-oncogenic roles have also been reported.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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