Thermo Fisher Scientific THEM2 Polyclonal Antibody

Applications

• Western Blot (WB): 0.25–0.5 µg/mL

Product Specifications

Target Information

THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver, and brain, and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism. The addition of StarD to THEM2 increases its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.