Thermo Fisher Scientific ORAI2 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 ORAI2 단클론 항체로 Western blot 및 IHC에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 1 mg/mL 농도로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific ORAI2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–248 of Human ORAI2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7) with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2549261 |
Product Specific Information
- Recommended positive controls: H1299
- Predicted reactivity: Mouse (94%), Rat (94%), Zebrafish (80%), Chicken (88%), Rhesus Monkey (99%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a four-transmembrane spanning protein essential for CRAC function. Like ORAI1, ORAI2 acts as a highly selective Ca++ plasma membrane channel gated by interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, though with lesser efficacy than ORAI1.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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