Thermo Fisher Scientific Phospho-TrkA (Ser791) Polyclonal Antibody
Phospho-TrkA (Ser791) 폴리클로날 항체로 인간, 생쥐, 랫트 시료에서 TrkA 인산화 상태 검출에 적합. Western blot 및 ICC/IF에 사용 가능. 고순도 친화 크로마토그래피 정제 제품으로, PBS/glycerol 완충액에 보관. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Suggested positive control: Rat or mouse brain cells
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:200
- Suggested positive control: HeLa cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine791 (P‑V‑Y(p)‑L‑D) derived from Human TrkA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20 °C |
| Shipping conditions | Wet ice |
| RRID | AB_2554280 |
Product Specific Information
A suggested positive control for Western blot is rat or mouse brain cells; suggested positive control for ICC/IF is HeLa cells.
Target Information
NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system.
TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway.
The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes.
Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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