
Thermo Fisher Scientific IPO5 Polyclonal Antibody
IPO5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat 등 다양한 종에 반응하며, 고순도 Affinity chromatography로 정제된 액상 항체입니다. 연구용으로만 사용 가능합니다.
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- PA5102541
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Thermo Fisher Scientific IPO5 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IPO5 (Accession O00410), corresponding to amino acid residues G795–I845 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851943 |
Product Specific Information
Antibody detects endogenous levels of total IPO5.
Target Information
Nucleocytoplasmic transport is a signal- and energy-dependent process occurring through nuclear pore complexes in the nuclear envelope. Proteins containing a nuclear localization signal (NLS) require the NLS import receptor, a heterodimer of importin alpha and beta subunits (karyopherins). Importin alpha binds NLS-containing cargo in the cytoplasm, while importin beta docks the complex at the nuclear pore. In the presence of nucleoside triphosphates and Ran GTPase, the complex translocates into the nucleus, where importin alpha enters with its cargo and importin beta remains at the pore. Interactions between importin beta and FG repeats of nucleoporins are essential for translocation. The IPO5 gene encodes a member of the importin beta family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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