Thermo Fisher Scientific SPINK5 Recombinant Rabbit Monoclonal Antibody (9Z2V3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

9Z2V3

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SPINK5 LEKTI. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SPINK5,uniProtId:Q9NQ38-1,ncbiNodeId:9606,antigenRange:100-200,antigenLength:1064,antigenImageFileName:MA5-55561_SPINK5_Q9NQ38-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55561_SPINK5_Q9NQ38-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: FKKGERDGDF ICPDYYEAVC GTDGKTYDNR CALCAENAKT GSQIGVKSEG ECKSSNPEQD VCSAFRPFVR DGRLGCTREN DPVLGPDGKT HGNKCAMCAE L

Target Information

Lympho-epithelial Kazal-type inhibitor (LEKTI) is a serine protease inhibitor which protects mucous epithelia against microbial attack and inflammation. LEKTI is a marker of epithelial differentiation and expresses strongly in the granular and uppermost spinous layers of the epidermis and differentiated layers of stratified epithelia. Defects in SPINK5, the gene encoding LEKTI, are the cause of Netherton syndrome, a severe autosomal recessive disorder characterized by atopic dermatitis, hayfever and other conditions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.