Thermo Fisher Scientific SPINK5 Recombinant Rabbit Monoclonal Antibody (9Z2V3)
SPINK5 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot 및 ELISA에 적합합니다. HEK293 세포에서 발현되었으며, Protein A로 정제된 고순도 항체입니다. 인간, 마우스, 랫트 시료에 반응하며, 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9Z2V3 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 100–200 of human SPINK5 (LEKTI) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
FKKGERDGDF ICPDYYEAVC GTDGKTYDNR CALCAENAKT GSQIGVKSEG ECKSSNPEQD VCSAFRPFVR DGRLGCTREN DPVLGPDGKT HGNKCAMCAE L
Target Information
Lympho-epithelial Kazal-type inhibitor (LEKTI) is a serine protease inhibitor that protects mucous epithelia against microbial attack and inflammation. LEKTI serves as a marker of epithelial differentiation and is strongly expressed in the granular and uppermost spinous layers of the epidermis and differentiated layers of stratified epithelia.
Defects in SPINK5, the gene encoding LEKTI, cause Netherton syndrome, a severe autosomal recessive disorder characterized by atopic dermatitis, hayfever, and related conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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