Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1/S2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1322)
SARS-CoV-2 스파이크 단백질 S1/S2를 타깃으로 하는 알파카 유래 재조합 단일클론 항체. ELISA, 중화시험, SPR 등 다양한 분석에 사용 가능. CHO 세포 발현, 1 mg/mL 농도, 금속 킬레이트 크로마토그래피로 정제. 연구용 한정 제품.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| ELISA (ELISA) | Assay-dependent | - |
| Neutralization (Neu) | Assay-dependent | - |
| Surface plasmon resonance (SPR) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1322 |
| Immunogen | Recombinant SARS-CoV-2 S/Spike glycoprotein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
Compatible with Direct ELISA.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus causing illnesses from mild cold symptoms to severe respiratory distress. The Spike (S) protein is crucial for viral attachment, fusion, and entry, serving as a key target for antibody, inhibitor, and vaccine development.
The receptor-binding domain (RBD) within the S1 subunit binds strongly to human and bat ACE2 receptors, exhibiting higher affinity compared to SARS-CoV.
SARS-CoV-2 S protein (1273 amino acids) includes:
- Signal peptide (1–13 aa)
- S1 subunit (14–685 aa) – receptor binding
- S2 subunit (686–1273 aa) – membrane fusion
The S-ECD represents the extracellular domain of the Spike protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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