Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1/S2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1009)

Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1/S2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1009)

Applications

• ELISA (Assay-dependent)

Product Specifications

Product Specific Information

• Compatible with Direct ELISA

Target Information

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The CoV Spike (S) protein is crucial for viral attachment, fusion, and entry, making it a key target for antibody development, entry inhibitors, and vaccines.

The Spike protein receptor-binding domain (RBD, S-RBD) binds strongly to human and bat ACE2 receptors, exhibiting higher affinity than SARS-CoV RBD.
S1 contains the RBD that specifically interacts with ACE2 receptors on host cells.
SARS-CoV-2 S protein consists of 1273 amino acids, including:

• Signal peptide (aa 1–13)
• S1 subunit (aa 14–685)
• S2 subunit (aa 686–1273)

The S-ECD represents the extracellular domain of the Spike protein.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.