Thermo Fisher Scientific Human WIZ Synthetic Peptide
인간 WIZ 단백질의 C-말단 17개 아미노산 서열에 대응하는 합성 펩타이드입니다. 항체 PA5-21082의 차단용 블로킹 펩타이드로 활용 가능하며, 고순도 정제된 액상 형태로 제공됩니다. PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide를 함유하며 -20°C에서 보관합니다.
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Thermo Fisher Scientific Human WIZ Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 17 amino acid sequence near the carboxy terminus of human WIZ.
PEP-1196 can be used as a blocking peptide with polyclonal antibody PA5-21082.
Target Information
WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen, and its expression was found in the granule cell layers of the cerebellum, dentate gyrus, and olfactory bulb.
Subsequent studies revealed that WIZ is ubiquitously expressed. It is a nuclear protein co-localizing with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions.
WIZ also associates with CtBP family proteins, known transcriptional co-repressors, and may link G9a/GLP complexes to CtBP co-repressor machinery, potentially regulating complex stability and gene silencing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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