Thermo Fisher Scientific CD36 Recombinant Mouse Monoclonal Antibody (185-1G2 (B467))
CD36 단백질에 특이적인 Thermo Fisher Scientific의 재조합 마우스 단일클론 항체로, 다양한 면역학적 분석(IHC, ICC/IF, Flow, IP, IA)에 사용 가능. 인간 CD36에 반응하며, HEK293 세포에서 발현된 IgM 형 항체. 1 mg/mL 농도, PBS 버퍼에 보관.
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Applications
- Immunohistochemistry (IHC): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
- Flow Cytometry (Flow): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
- Inhibition Assays (IA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 185-1G2 (B467) |
| Immunogen | Raised by immunizing mice with stimulated human leukocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage conditions | Store at 4°C short term; for long-term storage, keep at -20°C and avoid freeze/thaw cycles |
| Shipping conditions | Wet ice |
Product Specific Information
This antibody is specific against CD36 and recognizes an epitope between amino acids 155–183.
CD36 acts as a receptor for various ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine, and apoptotic cells.
It also functions as a receptor for hepatitis C virus in hepatocytes, facilitating cell entry and mediating uptake of M. fortuitum, E. coli, and S. aureus.
Target Information
CD36 (Scavenger Receptor Class B Member 3) is expressed on macrophages, platelets, adipocytes, and other cells.
It plays key roles in lipid metabolism, inflammation, and atherosclerosis, and is involved in recognition and uptake of oxidized LDL, long-chain fatty acids, and apoptotic cells.
CD36 also contributes to malaria pathogenesis and serves as a receptor for thrombospondin in platelets.
Mutations in CD36 cause Platelet Glycoprotein Deficiency and are associated with Coronary Heart Disease 7.
Multiple alternatively spliced transcript variants are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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