Thermo Fisher Scientific CD53 Monoclonal Antibody (MEM-53), FITC
CD53 단백질을 인식하는 Mouse IgG1 단클론 항체로 FITC 형광 표지. Flow cytometry와 IHC에 적합. 인간 시료에 검증됨. 4°C 암소 보관, 연구용 전용.
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Thermo Fisher Scientific CD53 Monoclonal Antibody (MEM-53), FITC
Applications
- Immunohistochemistry (IHC)
- Tested Dilution: -
- View 1 publication
- Flow Cytometry (Flow)
- Tested Dilution: 20 µL / 1×10⁶ cells
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-53 |
| Immunogen | Leukocytes of patient suffering from a LGL-type leukemia |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Storage conditions | 4°C, store in dark |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2534516 |
Additional Formats
Target Information
CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. It forms complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4, or tetraspanins CD37, CD81, and CD82, modulating various signaling processes. CD53 is involved in tumor cell radioresistance and exhibits anti-apoptotic effects. In the thymus, CD53 is up-regulated during T cell positive selection and strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, while neutrophil stimulation down-regulates CD53 expression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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