Thermo Fisher Scientific KLHL1 Polyclonal Antibody
인간 KLHL1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존됩니다. 신경 퇴행성 질환 연구 등에서 KLHL1 단백질 발현 분석에 활용 가능합니다.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human KLHL1. Recombinant protein control fragment (Product # RP-93583) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856281 |
Product Specific Information
Immunogen sequence:
SSSSFNPLNG TLLPVATRLQ QGAPGQGTQQ PARTLFYVES LEEEVVPGMD FPGPHEKGLV LQELKV
Target Information
The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of proteins that bind actin, form dimers, and act as actin-organizing proteins.
KLHL1 has been suggested to be involved in spinocerebellar ataxia type 8 (SCA8), as antisense RNA affecting KLHL1 expression has been observed in brain tissues of affected individuals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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