Thermo Fisher Scientific HTRA3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human HTRA3 protein. Validated for IHC (Paraffin) with dilution range 1:50–1:200. Antigen affinity purified and supplied as liquid in PBS with glycerol. Suitable for research use only; store at -20°C for long-term s...
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HTRA3 (Product #RP-91877) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856280 |
Product Specific Information
Immunogen sequence:
ITRFLTEFQD KQIKDWKKRF IGIRMRTITP SLVDELKASN PDFPEVSSGI YVQEVAPNSP SQRGGIQDGD IIVKVNGRPL VDSSELQEAV LTESPLLLEV RRGNDDLLFS IAP
Target Information
HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family, also known as pregnancy-related serine protease.
HtrA3 has two isoforms (long and short) produced by alternative splicing.
Similar to HtrA1, HtrA3 binds to various TGF-beta proteins and inhibits the signaling of BMP-4, BMP-2, and TGF-beta 1.
It does not inhibit signaling from a constitutively active BMP receptor, indicating inhibition occurs upstream of the cell surface receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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