Thermo Fisher Scientific Claudin 22/24 Polyclonal Antibody
Human Claudin 22/24 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 최적화됨. Affinity chromatography로 정제된 고순도 항체. PBS/glycerol buffer에 보관되며 -20°C에서 안정적 저장 가능. 연구용으로 다양한 암 관련 연구에 활용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Claudin 22/24 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691764 |
Target Information
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.
Differential expression of this gene has been observed in various malignancies, including:
- Breast cancer
- Ovarian cancer
- Hepatocellular carcinoma
- Urinary tumors
- Prostate cancer
- Lung cancer
- Head and neck cancers
- Thyroid carcinomas
Alternatively spliced transcript variants encoding different isoforms have been found.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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