Thermo Fisher Scientific Desmoglein 2 Monoclonal Antibody (10D2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

10D2

Immunogen

N terminal amino acids 37-164 of Human Desmoglein 2 fused to a proprietary tag. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Desmoglein 2 (DSG2),uniProtId:Q14126-1,ncbiNodeId:9606,antigenRange:37-164,antigenLength:1118,antigenImageFileName:MA5-36301_Desmoglein_2_DSG2_Q14126-1_House_mouse.svg,antigenImageFileNamePDP:MA5-36301_Desmoglein_2_DSG2_Q14126-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2896823

Product Specific Information

Tag sequence is: LLPKHPHLVR QKRAWITAPV ALREGEDLSK KNPIAKIHSD LAEERGLKIT YKYTGKGITE PPFGIFVFN KDTGELNVTS ILDREETPFF LLTGYALDAR GNNVEKPLEL RIKVLDIND NEPVFTQDVF

Immunogen sequence: LLPKHPHLVR QKRAWITAPV ALREGEDLSK KNPIAKIHSD LAEERGLKIT YKYTGKGITE PPFGIFVFNK DTGELNVTSI LDREETPFFL LTGYALDARGN NVEKPLELRI KVLDINDNEP VFTQDVF

Target Information

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.