Thermo Fisher Scientific Desmoglein 2 Monoclonal Antibody (10D2)
Human Desmoglein 2 인식하는 Mouse Monoclonal Antibody (Clone 10D2). Western blot, ICC/IF, IP 등 다양한 응용에 사용 가능. Protein A 정제, PBS 버퍼에 0.1% sodium azide 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:100 | |
| Immunocytochemistry (ICC/IF) | Assay-dependent | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10D2 |
| Immunogen | N-terminal amino acids 37–164 of Human Desmoglein 2 fused to a proprietary tag |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896823 |
Product Specific Information
Tag sequence:
LLPKHPHLVR QKRAWITAPV ALREGEDLSK KNPIAKIHSD LAEERGLKIT YKYTGKGITE PPFGIFVFN KDTGELNVTS ILDREETPFF LLTGYALDAR GNNVEKPLEL RIKVLDIND NEPVFTQDVF
Immunogen sequence:
LLPKHPHLVR QKRAWITAPV ALREGEDLSK KNPIAKIHSD LAEERGLKIT YKYTGKGITE PPFGIFVFNK DTGELNVTSI LDREETPFFL LTGYALDARGN NVEKPLELRI KVLDINDNEP VFTQDVF
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. Desmoglein 2 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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