Thermo Fisher Scientific 5HT2A Receptor Polyclonal Antibody, FITC
FITC로 결합된 5HT2A 수용체 폴리클로날 항체로, 인간·마우스·랫트 시료에 반응합니다. WB, IHC, ELISA, IP 등 다양한 응용에 적합하며, 고순도 친화 크로마토그래피 정제 제품입니다. -20°C 암소 보관이 권장됩니다.
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Thermo Fisher Scientific 5HT2A Receptor Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 400–450 on human 5-hydroxytryptamine receptor 2A |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Serotonin plays a major role in cardiovascular function and gastrointestinal motility. It mediates effects through G protein-coupled 5-HT receptors (SR receptors).
SR-2 receptors include three subtypes: SR-2A, SR-2B, and SR-2C, which activate phospholipase C and release intracellular calcium in response to serotonin.
- SR-2A: Involved in tracheal smooth muscle contraction, bronchoconstriction, aldosterone production, and associated with psychiatric disorders such as depression and schizophrenia.
- SR-2B: Expressed in cardiovascular tissues, gut, and brain; important in cardiac pathology.
- SR-2C: Mediates effects of atypical antipsychotic drugs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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