Thermo Fisher Scientific TRPML3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Mucolipin 3. Recombinant protein control fragment (Product #RP-91207). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRPML3,uniProtId:Q8TDD5-1,ncbiNodeId:9606,antigenRange:146-244,antigenLength:553,antigenImageFileName:PA5-53725_TRPML3_Q8TDD5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53725_TRPML3_Q8TDD5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644301

Product Specific Information

Immunogen sequence: YENKGTKQSA MAICQHFYKR GNIYPGNDTF DIDPEIETEC FFVEPDEPFH IGTPAENKLN LTLDFHRLLT VELQFKLKAI NLQTVRHQEL PDCYDFTLT

Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 87%.

Target Information

Expressed in the cochlea; particularly in the inner and outer hair cells. Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities and perinatal lethality. The phenotype varitin-waddler Jackcon (Va-J), which arose in a cross segregating for Va, is similar but less severe. Belongs to the transient receptor family, polycystin subfamily.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.