Thermo Fisher Scientific Human DDX60 Synthetic Peptide
인간 DDX60 단백질의 중심부 17개 아미노산 서열로 구성된 합성 펩타이드입니다. 항체 PA5-34442의 블로킹 펩타이드로 사용 가능합니다. 순도 높은 액상 형태로 제공되며, PBS 버퍼(pH 7.2)와 0.1% BSA, 0.02% sodium azide를 포함합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PEP1484
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the center of human DDX60.
PEP-1484 can be used as a blocking peptide with polyclonal antibody PA5-34442.
Target Information
DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of the RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2.
These proteins activate TBK1 and IKK-ε, signaling IRF3 and NF-κB-responsive genes in the innate immune response pathway.
DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection but is dispensable for TLR3-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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