Thermo Fisher Scientific Granzyme K Monoclonal Antibody (GM24C3)
Granzyme K 단백질을 인식하는 GM24C3 마우스 단클론 항체로, Flow Cytometry와 ELISA에 적합합니다. 인간 Granzyme K cDNA를 면역원으로 사용하며 비결합형 액상 형태입니다. 세포 사멸 연구 및 면역학적 분석용 연구 전용 시약입니다.
- 카탈로그번호
- MA117753
- 판매단위
- pk
카탈로그
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1.2 µg/1×10^6 cells
ELISA (ELISA)
- Tested Dilution: 1:200–1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GM24C3 |
| Immunogen | cDNA encoding human Granzyme K |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2247979 |
Product Specific Information
This antibody recognizes native Granzyme K protein expressed in transfected mammalian cells.
Target Information
Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localized in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11–12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specificity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen, and peripheral blood leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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