Thermo Fisher Scientific Granzyme K Monoclonal Antibody (GM6C3)
Granzyme K 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry 및 ELISA에 적합합니다. 비결합형 액상 포맷이며 2 mg/mL 농도로 제공됩니다. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 냉동 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Flow Cytometry (Flow) | 1.2 µg / 1×10⁶ cells | - |
| ELISA (ELISA) | 1:200–1:400 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GM6C3 |
| Immunogen | cDNA encoding human Granzyme K |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2114821 |
Product Specific Information
This antibody recognizes native Granzyme K protein expressed in transfected mammalian cells.
It can be used in a Sandwich ELISA as a detection antibody with Product # MA1-17754 as a capture antibody.
Target Information
Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localized in the cytotoxic granules of activated T cells and NK cells.
It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11–12, close to the granzyme A-encoding gene.
Like granzyme A, it has trypsin-like specificity, cleaving at basic residues arginine and lysine.
Granzyme K triggers rapid cell death independently of caspase activation, causing single-stranded DNA nicks.
It is primarily expressed in thymus, lung, spleen, and peripheral blood leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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