Thermo Fisher Scientific GRB10 Polyclonal Antibody
Human GRB10 단백질을 인식하는 염소 유래 polyclonal 항체로, Western blot에 적합합니다. 0.5 mg/mL 농도의 액상 형태이며, TBS buffer(pH 7.3, 0.5% BSA)로 보관됩니다. 연구용으로만 사용되며 -20°C에서 보관하십시오.
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Thermo Fisher Scientific GRB10 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-AQSDRLANHQEDDV (aa 37–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933005 |
Product Specific Information
- This antibody is expected to recognise the reported isoforms (NP_005302.3; NP_001001549.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus.
A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7.
GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment but appears to bind poorly to the EGF receptor.
GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same chromosome near the EGF receptor-related protein HER2.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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