Thermo Fisher Scientific Gephyrin Polyclonal Antibody
Rabbit polyclonal antibody targeting human Gephyrin protein. Suitable for WB and IP applications. High specificity, antigen-affinity purified, liquid form. Predicted cross-reactivity with mouse, rat, and chicken. For research use only.
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Thermo Fisher Scientific Gephyrin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 686 to 736 of human Gephyrin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse, Rat, and Chicken
Target Information
Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high-affinity binding to receptor subunit domains and tubulin dimers.
In non-neuronal tissues, it is required for molybdenum cofactor biosynthesis.
Mutations in this gene may be associated with hyperplexia and molybdenum cofactor deficiency.
Numerous alternatively spliced transcript variants encoding different isoforms have been described, though the full-length nature of all variants is not fully known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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