Thermo Fisher Scientific ATG9A Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Target Information

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells. It is responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation.
Macroautophagy involves the formation of double-membrane bound autophagosomes that enclose cytoplasmic constituents targeted for degradation. These autophagosomes then fuse with lysosomes (or vacuoles), releasing single-membrane bound autophagic bodies which are subsequently degraded.
Apg9 plays a direct role in the formation of cytoplasm-to-vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.