Thermo Fisher Scientific FGFR1 Polyclonal Antibody
FGFR1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 사용 가능. 사람, 생쥐, 랫트에 반응하며 고순도 정제. 연구용으로 세포 성장 및 분화 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 118–160 of Human FGFR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2803377 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor family (FGFR1–4), which are membrane-spanning tyrosine kinases serving as high-affinity receptors for 17 growth factors (FGF1–17).
These receptors play critical roles in mesoderm induction, cell growth and migration, organ formation, and bone development.
FGFR1 undergoes alternative splicing, producing multiple variants expressed differently during embryonic development and in adulthood.
Mutations or aberrations in FGFR1 are linked to several diseases, including Pfeiffer syndrome, idiopathic hypogonadotropic hypogonadism, Kallmann syndrome type 2, osteoglophonic dysplasia, Jackson-Weiss syndrome, Antley-Bixler syndrome, and chromosomal abnormalities associated with stem cell myeloproliferative disorders and leukemia-lymphoma syndromes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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