Thermo Fisher Scientific IL1F6 Monoclonal Antibody (OTI3A12), TrueMAB
IL1F6 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, Western blot과 Immunocytochemistry에 최적화됨. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제, 안정적 액상 형태로 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A12 |
| Immunogen | Full-length human recombinant IL1F6 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.42 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The IL-1 family consists of 11 structurally related ligands, including IL-36α (IL-1F6), IL-36β (IL-1F8), and IL-36γ (IL-1F9).
IL-36α is highly expressed in psoriatic plaques and uniquely expressed by T cells, monocytes, and B cells. It is primarily found in skin and lymphoid tissues, with lower levels in fetal brain, trachea, stomach, and intestine.
IL-36α signals through IL-1Rrp2 (IL-1R6) and IL-RAcP receptors, activating NF-κB and MAPK pathways, and inducing proinflammatory cytokines such as IL-6, IL-8, BD-2, and BD-3.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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배송/결제/교환/반품 안내
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