Thermo Fisher Scientific FAM120B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FAM120B. Recombinant protein control fragment (Product #RP-94701). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FAM120B,uniProtId:Q96EK7-1,ncbiNodeId:9606,antigenRange:573-658,antigenLength:910,antigenImageFileName:PA5-57984_FAM120B_Q96EK7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57984_FAM120B_Q96EK7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641239

Product Specific Information

Immunogen sequence: DTEILKVART HHVQAESYLV YNIMSSGEIE CSNTLEDELD QALPSQAFIY RPIRQRVYSL LLEDCQDVTS TCLAVKEWFV YPGNPL

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 83%.

Target Information

The transcription factor peroxisome proliferator-activated receptor -gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.