Thermo Fisher Scientific FAM120B Polyclonal Antibody
FAM120B 단백질을 표적으로 하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. 인간 시료에 반응하며 IHC(P)에서 1:500~1:1000 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태로, 연구용으로 적합.
- 카탈로그번호
- PA557984
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAM120B (Recombinant protein control fragment: Product #RP-94701) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641239 |
Product Specific Information
- Immunogen sequence:
DTEILKVART HHVQAESYLV YNIMSSGEIE CSNTLEDELD QALPSQAFIY RPIRQRVYSL LLEDCQDVTS TCLAVKEWFV YPGNPL - Highest antigen sequence identity:
- Mouse: 80%
- Rat: 83%
Target Information
The transcription factor peroxisome proliferator-activated receptor-gamma (PPARγ) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association with various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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