Thermo Fisher Scientific FAM120B Polyclonal Antibody
Thermo Fisher Scientific의 FAM120B Polyclonal Antibody는 인간 FAM120B 단백질을 타겟으로 하는 토끼 IgG 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: [참고 없음]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
- Publications: [참고 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAM120B. Recombinant protein control fragment (Product #RP-94700). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641240 |
Product Specific Information
Immunogen sequence:
EVPMYTGSEP RQEVPMYTGP ESRQEVPMYT GPESRQEVLI RTDPESRQEI MCTGHESKQE VPICTDPISK QEDSMCTHAE INQKLPVATD FEFKLEALMC TNPEIKQEDP TNV
- Highest antigen sequence identity to orthologs:
- Mouse: 55%
- Rat: 48%
Target Information
The transcription factor peroxisome proliferator-activated receptor-gamma (PPARγ) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association with various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, while knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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