Thermo Fisher Scientific Thyroglobulin Monoclonal Antibody (CL0164)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

CL0164

Immunogen

Recombinant Protein corresonding to Human Thyroglobulin if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Thyroglobulin,uniProtId:P01266-1,ncbiNodeId:9606,antigenRange:1304-1466,antigenLength:2768,antigenImageFileName:MA5-34965_Thyroglobulin_P01266-1_House_mouse.svg,antigenImageFileNamePDP:MA5-34965_Thyroglobulin_P01266-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.00 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2848870

Product Specific Information

Immunogen sequence: KMCSADYADL LQTFQVFILD ELTARGFCQI QVKTFGTLVS IPVCNNSSVQ VGCLTRERLG VNVTWKSRLE DIPVASLPDL HDIERALVGK DLLGRFTDLI QSGSFQLHLD SKTFPAETIR FLQGDHFGTS PRTWFGCSEG FYQVLTSEAS QDGLGCVKCP EGS

Target Information

The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.