Thermo Fisher Scientific PPP2R1B Monoclonal Antibody (OTI8B6), TrueMAB
PPP2R1B 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 IHC(P) 분석에 적합합니다. Human, Mouse, Rat에 반응하며, Lyophilized 형태로 제공됩니다. 연구용으로 단백질 인산화 조절 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B6 |
| Immunogen | Human recombinant protein fragment (aa 19–601 of human PPP2R1B) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
In eukaryotic cells, phosphorylation and dephosphorylation of serine and threonine residues regulate key cellular functions such as division, homeostasis, and apoptosis. Protein phosphatases, including PP1, PP2A, PP2B (calcineurin), and PP2C, play crucial roles in these processes. The PP2A family includes catalytic subunits PP2A alpha and beta, which associate with various regulatory subunits such as PP2A-A, PP2A-B, PP2A-C, and PP2A-B56 isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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