Thermo Fisher Scientific FABP7 Polyclonal Antibody
FABP7 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 사용 가능. 인간, 마우스, 랫트 시료에 반응하며, 고순도 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관되며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FABP7 (Accession O15540), corresponding to amino acid residues V93–A132. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852048 |
Product Specific Information
Antibody detects endogenous levels of total FABP7.
Target Information
FABP7 was initially isolated from a human fetal brain cDNA library. Its mRNA is expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene belongs to the fatty acid binding protein (FABPs) family—small, highly conserved cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands.
FABPs are involved in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and plays a crucial role in maintaining neuroepithelial cells during early cortical development. It is also frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression reduces in vitro cell proliferation and Matrigel invasion, suggesting FABP7 as a potential diagnostic and therapeutic target.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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