Thermo Fisher Scientific Phospho-BLK (Tyr389) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human BLK (Phospho-Tyr389) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BLK,uniProtId:P51451-1,ncbiNodeId:9606,antigenRange:375-397,antigenLength:505,antigenImageFileName:PA5-64566_BLK_P51451-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64566_BLK_P51451-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 30% glycerol

Contains

0.01% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2662931

Product Specific Information

Phospho-BLK (Tyr389) Polyclonal Antibody detects endogenous levels of BLK only when phosphorylated at Tyr389.

Target Information

B-lymphoid tyrosine kinase (BLK) is a non-receptor tyrosine kinase that belongs to the Src family of kinases. BLK plays an important role in B-cell activation. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.