Thermo Fisher Scientific Laminin beta-2 Polyclonal Antibody
Thermo Fisher Scientific의 Laminin beta-2 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 고품질 항체로, WB 및 ICC/IF에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5103211
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- View 1 publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LAMB2 (Accession P55268), corresponding to amino acid residues G72–A122 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852578 |
Product Specific Information
Antibody detects endogenous levels of total LAMB2.
Target Information
Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane.
Two main subtypes of nuclear lamins can be distinguished: A-type lamins and B-type lamins.
A-type lamins include lamin A, lamin C, and lamin Adel 10, while B-type lamins include lamin B1 and lamin B2.
Mutations in A-type lamins are associated with genetic disorders such as Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease, and Dunnigan-type familial partial lipodystrophy.
A-type lamins are linked to cell differentiation and chromatin interaction, suggesting a role in differential gene expression regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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