Thermo Fisher Scientific CLEC5A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1.0 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Immunogen sequence: NTPEKLKFLQ DITDAEKYFI GLIYHREEKR WRWINNSVFN GNVTNQNQNF (aa 110-159). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CLEC5A,uniProtId:Q9NY25-1,ncbiNodeId:9606,antigenRange:110-159,antigenLength:188,antigenImageFileName:PA5-114187_CLEC5A_Q9NY25-1_Rabbit.svg,antigenImageFileNamePDP:PA5-114187_CLEC5A_Q9NY25-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2884701

Product Specific Information

Immunogen sequence: NTPEKLKFLQ DITDAEKYFI GLIYHREEKR WRWINNSVFN GNVTNQNQNF

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Predicted homology: Cow: 93%; Dog: 86%; Horse: 86%; Human: 100%; Pig: 79%; Rat: 79%; Yeast: 83%

Target Information

Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.