Thermo Fisher Scientific ADAT3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1.0 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: RPFPACSFAP AAAPQAVRAG AVRKLDADED GLPYLCTGYD LYVTREPCAM
• For short-term use, store at 2–8°C up to 1 week.
• For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted homology: Human 100%

Target Information

The ADAT3 gene encodes a subunit of a tRNA-specific adenosine deaminase.
This heterodimeric enzyme converts adenosine to inosine in the tRNA anticodon.
Mutations in this gene are associated with a syndrome characterized by intellectual disability and strabismus.
The gene shares its 5′ exon with the overlapping gene secretory carrier membrane protein 4.

Associated Diseases:

• Neurodevelopmental disorder with brain abnormalities, poor growth, and dysmorphic facies
• Cone-rod dystrophy 10

Related Pathways:

• tRNA processing
• Processing of capped intron-containing pre-mRNA

Gene Ontology (GO) Annotations:

• Hydrolase activity

Paralog: ADAT2

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.